Certified Diabetes Care and Education Specialist (CDCES) Practice Exam

An overweight woman with type 2 diabetes is motivated to lose weight. In addition to lifestyle interventions, which treatment is the best recommendation for her?

1. Glyburide

2. Detemir

3. Saxagliptin

4. Liraglutide

The correct answer is: Liraglutide

Liraglutide is recommended as the best treatment for this overweight woman with type 2 diabetes who is motivated to lose weight because it is associated with weight loss benefits in addition to its glucose-lowering effects. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that not only helps improve glycemic control but also provides the extra benefit of promoting weight loss, making it a suitable option for individuals who are overweight or obese. The mechanism of action of Liraglutide includes slowing gastric emptying, reducing appetite, and increasing feelings of fullness, all of which contribute to weight loss. This is particularly advantageous for individuals with type 2 diabetes, as weight loss can enhance insulin sensitivity and overall diabetes management. In contrast, while the other medications listed may help manage blood glucose levels, they do not have the same significant impact on weight loss. Glyburide is a sulfonylurea that can potentially lead to weight gain. Detemir is a long-acting insulin that primarily focuses on blood glucose control without addressing weight management. Saxagliptin, a DPP-4 inhibitor, is also less associated with weight loss compared to Liraglutide. Therefore, L